Model Reconstruction for Moment-Based Stochastic Chemical Kinetics
نویسندگان
چکیده
منابع مشابه
Validity conditions for moment closure approximations in stochastic chemical kinetics.
Approximations based on moment-closure (MA) are commonly used to obtain estimates of the mean molecule numbers and of the variance of fluctuations in the number of molecules of chemical systems. The advantage of this approach is that it can be far less computationally expensive than exact stochastic simulations of the chemical master equation. Here, we numerically study the conditions under whi...
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In recent years, moment-closure approximations (MAs) of the chemical master equation have become a popular method for the study of stochastic effects in chemical reaction systems. Several different MA methods have been proposed and applied in the literature, but it remains unclear how they perform with respect to each other. In this paper, we study the normal, Poisson, log-normal, and central-m...
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where k is the rate constant. The stochastic approach to chemical kinetics is concerned with modeling chemical reactions in situations where the assumptions underlying equations of this type break down. In order to illustrate this, suppose that the reaction above is occuring in a drop of water of volume V , which contains only a very small number, say 3, of molecules of I. The kinetic equation ...
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ژورنال
عنوان ژورنال: ACM Transactions on Modeling and Computer Simulation
سال: 2015
ISSN: 1049-3301,1558-1195
DOI: 10.1145/2699712